Vaccine name: Murine TYRP2 Plasmid DNA Vaccine
Type: DNA vaccine
Status: Clinical trial
Host Species: Human
Description: A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities. Upon administration, murine TYRP2 plasmid DNA vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing TYRP2; this vaccine may also induce an immune response against tyrosinase-related protein-1 (TYRP1). TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated in melanoma cells, are involved in melanin synthesis. (NCIT_C77877).
Immunization Route: n/a
PubMed: n/a
PumMed Link: n/a
Gene/protein: n/a
VIOLIN Link: http://www.violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5310&keywords=Murine%20TYRP2%20Plasmid%20DNA%20Vaccine
Vaccine name: Murine TYRP2 Plasmid DNA Vaccine Type: DNA vaccine Status: Clinical trial Host Species: Human Description: A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities. Upon administration, murine TYRP2 plasmid DNA vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing TYRP2; this vaccine may also induce an immune response against tyrosinase-related protein-1 (TYRP1). TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated in melanoma cells, are involved in melanin synthesis. (NCIT_C77877). Immunization Route: n/a PubMed: n/a PumMed Link: n/a Gene/protein: n/a VIOLIN Link: http://www.violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5310&keywords=Murine%20TYRP2%20Plasmid%20DNA%20Vaccine