search

vaccineontology / VO

Vaccine Ontology
https://obofoundry.org/ontology/vo.html
15 stars 9 forks source link

VAC: LTA1 #567

Closed wolfgang-leitner closed 2 years ago

wolfgang-leitner commented 3 years ago

Request to add a new vaccine adjuvant as seen in VAC: https://vac.niaid.nih.gov/view?id=44

Chemical Nature: (1) Protein Mechanism of Action: cAMP, inflammasome induction Immune profile induced: mixed Th1/Th2/Th17 Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces epitope spreading, (3) Promotes antibody affinity maturation, (4) Promotes antibody epitope spreading, (5) High stability Route of immunization: IM, IN, SL, ID, IP Point of Contact: Elizabeth Norton, Tulane University

Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=6957164 https://www.ncbi.nlm.nih.gov/pubmed/?term=22526674 https://www.ncbi.nlm.nih.gov/pubmed/?term=26305793 https://www.ncbi.nlm.nih.gov/pubmed/?term=31427449 https://www.ncbi.nlm.nih.gov/pubmed/?term=31641151 https://www.ncbi.nlm.nih.gov/pubmed/?term=31929548 https://www.ncbi.nlm.nih.gov/pubmed/?term=33986280 https://www.ncbi.nlm.nih.gov/pubmed/?term=34516780

yongqunh commented 2 years ago

We have assigned a VO ID: VO_0005355, to this adjuvant. See more here: http://purl.obolibrary.org/obo/VO_0005355

yongqunh commented 2 years ago

I checked Ontobee and found the VO vaccine adjuvant term is now loaded well. So I am going to close this issue.