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vaccineontology / VO

Vaccine Ontology
https://obofoundry.org/ontology/vo.html
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VAC: SMNP #632

Closed nkosar closed 11 months ago

nkosar commented 1 year ago

Request to add a new vaccine adjuvant as seen in VAC: https://vac.niaid.nih.gov/view?id=77

Chemical Nature: Combination adjuvant Mechanism of Action: Cytokine induction in draining lymph nodes with increased lymph flow and lymph antigen accumulation Immune profile induced: Mixed Th1/Th2

Route of immunization: s.c. / i.m. / i.n. Point of Contact: Katarzyna Kaczmarek Michaels, Massachusetts Institute of Technology

Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=34860581 https://www.ncbi.nlm.nih.gov/pubmed/?term=36131022 https://www.ncbi.nlm.nih.gov/pubmed/?term=34878851

Ongoing clinical trials: n/a

zhengj2007 commented 11 months ago

Hi @nkosar, I am working on the term you submitted. Could you please add the definition? Thanks!

nkosar commented 11 months ago

@zhengj2007 definition would be " AS01-mimic, Immune Stimulating Complex (ISCOM) with a TLR4 agonist"

zhengj2007 commented 11 months ago

Added in VO, with ID: VO_0006095