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vaccineontology / VO

Vaccine Ontology
https://obofoundry.org/ontology/vo.html
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VAC: SLA-Alum #651

Closed nkosar closed 10 months ago

nkosar commented 10 months ago

Request to add a new vaccine adjuvant as seen in VAC: https://vac.niaid.nih.gov/view?id=82

Chemical Nature: • Synthetic derivative of natural compound • Combination adjuvant • Mineral salt

Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased

Route of immunization: IM Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI)

Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=26901122 https://www.ncbi.nlm.nih.gov/pubmed/?term=32983577

Ongoing clinical trials: none

zhengj2007 commented 10 months ago

Hi @nkosar, I am working on the term you submitted. Could you please add the definition? Thanks!

nkosar commented 10 months ago

@zhengj2007 definition "combination adjuvant of a synthetic TLR4 agonist and aluminum salt"

zhengj2007 commented 10 months ago

Added in VO, with ID: VO_0006100

nkosar commented 10 months ago

@zhengj2007 Hi, this might be a problem on my end but when I try accessing the VO ID it tells me that the term was not found. Let me know if this is a general issue or if only on my end. https://ontobee.org/ontology/VO?iri=http://purl.obolibrary.org/obo/VO_0006100

zhengj2007 commented 10 months ago

@nkosar The term is added. However, you cannot find it on the website until we make the VO release and load it into the ontobee. I will contact @yongqunh for the following steps.

zhengj2007 commented 10 months ago

@nkosar Could you please try the link: http://purl.obolibrary.org/obo/VO_0006100

nkosar commented 10 months ago

@zhengj2007 this link worked, thanks!