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vaccineontology / VO

Vaccine Ontology
https://obofoundry.org/ontology/vo.html
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VAC: ACM-CpG #690

Closed nkosar closed 7 months ago

nkosar commented 8 months ago

Request to add a new vaccine adjuvant as seen in VAC: https://vac.niaid.nih.gov/view?id=92

Chemical Nature: Nucleic acid, Emulsion Mechanism of Action: Innate Immune Activation, preferential uptake by APCs Immune profile induced: Th1-biased Definition: TLR-agonist for target; nucleic acid-based adjuvant for chemical nature

Route of immunization: SQ, IN, IM Point of Contact: Madhavan Nallani, ACM Biolabs

Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=34618423 https://www.ncbi.nlm.nih.gov/pubmed/?term=36223228

Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT05385991

nkosar commented 8 months ago

More description for composition: this is both, a nucleic acid adjuvant AND an emulsion (DNA in an emulsion).

zhengj2007 commented 7 months ago

Assigned ID: VO_0006106