female sex determination is correct, but called as error

varfish-org / varfish-server

VarFish: comprehensive DNA variant analysis for diagnostics and research

MIT License

43 stars 11 forks source link

female sex determination is correct, but called as error #1623

Open flokraft85 opened 6 months ago

flokraft85 commented 6 months ago

Describe the bug As QC feature VarFish compare the sex of the ped file with the het. call ratio on chromosome X. Althoug males and females are cluster on the rigth side of the plot, females are shown in red and as error.

To Reproduce Steps to reproduce the behavior:

Open a case
click on Quality Control

Expected behavior Females should be not calles as "error".

Screenshots grafik

xiamaz commented 6 months ago

@flokraft85 Which mehari version did you use for annotation?

flokraft85 commented 6 months ago

Hi @xiamaz, we use the latest version. 0.25.5.

Best, Florian

xiamaz commented 6 months ago

@holtgrewe mehari version should be fine. Any other ideas?