vastgroup / vast-tools

A toolset for profiling alternative splicing events in RNA-Seq data.
MIT License
77 stars 29 forks source link

How to determine that a variable clipping event is a difference variable clipping event? #122

Open happypiggyzjx opened 3 months ago

happypiggyzjx commented 3 months ago

Dear VAST-TOOLS development team: Thank you for developing such a convenient and fast software. While analyzing the data, I encountered a problem: How does MAJIQ determine that a variable clipping event is a differential variable clipping event? Can I understand that as long as 0.05 ≤ PSI ≤ 0.95 and |ΔPSI| > 0.2, the event is considered to be a differential variable clipping event for the two samples used for comparison?

Can you please give the judgment criteria for DAS systematically? Thank you and sincerely look forward to your professional reply.

happypiggy