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HyPhy standalone analyses
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Question Regarding Relax Analysis Results (K = 0) #60

Open aaannaw opened 13 hours ago

aaannaw commented 13 hours ago

Dear author, Based on the results of the RELAX analysis, I observed evidence of relaxation (K < 1) or intensification (K > 1) of selection on the test branches compared to the reference branches. However, I noticed that for some genes, K is exactly equal to 0, which might suggest extreme relaxation. I would like to confirm if this interpretation is accurate or if it might indicate a potential issue in the analysis or data.

Thank you for your guidance.

Best regards, Na Wan

spond commented 13 hours ago

Dear @aaannaw,

Generally K=0 is indicative of some sort of convergence or model fit issue. Can you provide an example?

  1. The relax command you ran.
  2. The input files.
  3. The output your observed on the screen.

Best, Sergei