vgteam / vg

tools for working with genome variation graphs
https://biostars.org/tag/vg/
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How to align both long and paired end short reads using vg #4282

Closed nathanLauHKGI closed 1 month ago

nathanLauHKGI commented 1 month ago

Hi there

This is another clarification question:

Is there a recommended way align both long and paired end short reads using vg?

jeizenga commented 1 month ago

Paired-end short reads are fully supported. To access the paired-end features, you can use two -f arguments to provide the R1 and R2 reads. We are currently developing long-read alignment support, but these features are still experimental. You shouldn't yet expect a consistent interface or consistent performance for giraffe's long-read mapping.