AmpliconArchitect (AA) is a tool to identify one or more connected genomic regions which have simultaneous copy number amplification and elucidates the architecture of the amplicon. In the current version, AA takes as input next generation sequencing reads (paired-end Illumina reads) mapped to the hg19/GRCh37 reference sequence and one or more regions of interest. Please "watch" this repository for improvements in runtime, accuracy and annotations for GRCh38 human reference genome coming up soon.
Other
131
stars
42
forks
source link
Conflict between web visualization interface and circle files #66
So, I know I have the circle3 include 44+ and 45+ located in chr17. Then I upload this file to http://genomequery.ucsd.edu:8800/ to visualization, but what puzzles me is
the output graph show the ciecle3 located in chr8.
So, Could you please give me more information about it. Thanks for your attention.
Best.
Zhang.
After discussing with Zhang in a separate thread, I believe this is an issue caused by the cycle_visualization tool not supporting hg38 output from my fork. I have not yet tried to update this visualization method to support hg38.
Dear, I have used AmpliconArchitect to calculate ecDNA,and I got the output store in {sample}_circle.txt, It is look like this:
So, I know I have the circle3 include 44+ and 45+ located in chr17. Then I upload this file to http://genomequery.ucsd.edu:8800/ to visualization, but what puzzles me is the output graph show the ciecle3 located in chr8.
So, Could you please give me more information about it. Thanks for your attention. Best. Zhang.