Dental Biofilm Microbiota Dysbiosis Is Associated With the Risk of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

[SvetlanaUP]

Dental Biofilm Microbiota Dysbiosis Is Associated With the Risk of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation – Vitor Heidrich et al. – Frontiers in Immunology 2021

https://www.frontiersin.org/articles/10.3389/fimmu.2021.692225/full

[Gboladee]

Name: Agbolade Adeniji May I please have this paper assigned to me

[SvetlanaUP]

Assigned.

[Analyst-Joan]

Joan C. Chukwuemeka

Good morning @SvetlanaUP @lwaldron Please can I be assigned this article for curation? Thanks

[Analyst-Joan]

Good day @cmirzayi @SvetlanaUP @lwaldron

I have completed the curation for this article.

You can find the BugSigDB link at Study_904 for your review.

Looking forward to make changes or improvements that will be required, If any.

Thank you. Joan C. Chukwuemeka [Joan Chuks]

[Omabekee]

A near-perfect curation! @Analyst-Joan Fantastic!⭐ Some points to take note:

1. It's good for source descriptions (for signatures) to be descriptive enough so that anyone who comes across the study in the future can immediately tell what's going on without going too deep into the whole curation.
2. It's okay to curate experiments with alpha diversity and no differential abundance results, in such cases, the experiment (s) will not have signatures.

CURATION RESULTS

1. All elements marked "Needs review" (none "Incomplete") (1 point): 1
2. Correct study design (1 point): 1
3. Entered all relevant experiments and no irrelevant experiments (1 point): 0.5
4. Body site correctly identified (i.e. does not include multiple sites) (1 point): 1
5. Condition entered according to contrast (correct EFO ontology) (1 point): 1
6. Contrast groups correctly identified (1 point): 1
7. Groups correctly labeled as 1 and 0 (1=cases, 0=controls) (1 point): 1
8. Antibiotic exclusion correctly identified (1 point): 1
9. Correctly identified sequencing details (2 points): 2
10. Identified correct statistical test (1 point): 1
11. Identified MHT correction (1 point): 1
12. Correctly recorded matched on factors (1 point): 1
13. Entered correct number of statistical tests per experiment (1 point): 1
14. All diversity measures identified (1 point): 1
15. Diversity results correctly entered as increased/decreased/unchanged (1 point): 1
16. All signature sources correctly identified (-1 for each error) (2 points): 2
17. Abundance direction correctly selected (1 point): 1
18. Members of Signatures identified correctly (2 points): 2
19. Correct use of NCBI taxonomy (2 points): 2

Total: 22.5

@SvetlanaUP , review of Study 904 complete. ✅

[Analyst-Joan]

Good morning @Omabekee Thanks a lot for the feedback. I've gone through the curation on BugSigDB Study_904 and noted down the improvements you made.👍 I'd be sure to implement this in my future curation.😊