Alterations in gut microbiota and metabolite profiles in patients with infantile cholestasis

[Folakunmi21]

Alterations in gut microbiota and metabolite profiles in patients with infantile cholestasis - Jin et al - BMC https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-023-03115-1

[AmaraLewa]

I will like to have this paper assigned to me please. My full name is Amarachi Lewachi

[SvetlanaUP]

Ready for review https://bugsigdb.org/Study_933

[AmaraLewa]

Hi. I am done curating and would love my paper to be reviewed. Thank you @Lonercode

Ready for review https://bugsigdb.org/Study_933

[Peacesandy]

Hi @AmaraLewa this is a good first curation attempt, however here are some few points to note. ✍️

• The body site you entered is incorrect.
• The condition you entered is incorrect
• you did not enter a significance threshold
• you did not correctly record the matched on factor
• Members of Signatures were not identified correctly
• The curatable signature can be gotten from Figure 1c, you just entered Figure 1, which also has relative abundance and Heatmap of KEGG pathway enrichment analysis

N/B; The study has been corrected and reviewed

CURATION RESULTS

All elements marked "Needs review" (none "Incomplete") (1 point): 1 Correct study design (1 point): 1 Entered all relevant experiments and no irrelevant experiments (1 point): 1 Body site correctly identified (i.e. does not include multiple sites) (1 point): 0 Condition entered according to contrast (correct EFO ontology) (1 point): 0 Contrast groups correctly identified (1 point): 1 Groups correctly labeled as 1 and 0 (1=cases, 0=controls) (1 point): 1 Antibiotic exclusion correctly identified (1 point): 1 Correctly identified sequencing details (2 points): 2 Identified correct statistical test (1 point): 1 Identified MHT correction (1 point): 1 Correctly recorded matched on factors (1 point): 0 Entered correct number of statistical tests per experiment (1 point): 1 All diversity measures identified (1 point): 1 Diversity results correctly entered as increased/decreased/unchanged (1 point): 1 All signature sources correctly identified (-1 for each error) (2 points): 1 Abundance direction correctly selected (1 point): 1 Members of Signatures identified correctly (2 points): 1 Correct use of NCBI taxonomy (2 points): 2

Total (maximum 23 points): 18

@SvetlanaUP https://bugsigdb.org/Study_933 reviewed and corrected ✅