Dysbiosis of skin microbiome and gut microbiome in melanoma progression

[SvetlanaUP]

Dysbiosis of skin microbiome and gut microbiome in melanoma progression – Chahrazed Mekadim – BMC Microbiology https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-022-02458-5

[jumokeadeoyo]

Hi, I would love to curate this paper

[nityasinghal-14]

Hello @jumokeadeoyo , I see you have been assigned this curation. Would you be open to collaborating? I'm looking forward to it, thank you.

[snehuman]

can I be assigned this?

[SvetlanaUP]

Assigned to @snehuman

[snehuman]

I have tried to curate the complete study as per my knowledge, I would like you to review it. Thank you. https://bugsigdb.org/Study_991

[SvetlanaUP]

Item	Description	max	points
1	All elements marked "Needs review" (none "Incomplete")	1	1
2	Correct study design	1	0
3	Entered all relevant experiments and no irrelevant experiments	1	0
4	Body site correctly identified (i.e. does not include multiple sites)	1	1
5	Condition entered according to contrast (correct EFO ontology)	1	1
6	Contrast groups correctly identified	1	0.5
7	Groups correctly labeled as 1 and 0 (1=cases, 0=controls)	1	0.5
8	Antibiotic exclusion correctly identified	1	1
9	Correctly identified sequencing details	2	2
10	Identified correct statistical test	1	0.5
11	Identified MHT correction	1	1
12	Correctly recorded matched on factors	1	0
13	Entered correct number of statistical tests per experiment	1	0.5
14	All diversity measures identified	1	0
15	Diversity results correctly entered as increased/decreased/unchanged	1	0.5
16	All signature sources correctly identified (-1 for each error)	2	0
17	Abundance direction correctly selected	1	0
18	Members of signatures identified correctly	2	0
19	Correct use of NCBI taxonomy	2	0
	TOTAL	23	9.5

• not defined study design
• incorrect use of NCBI taxonomy
• not identified correct sources of signatures nor experiments
• and more errors to correct

[SvetlanaUP]

Isioma20 you could help out here in correction of this incomplete curation.

[Isioma20]

Would work it and make all the necessary corrections per the feedback. Thank you!

[Isioma20]

the changes I made to this curation include -changed the study design -added all the relevant experiments including those with significant alpha diversity results -identified signature sources and curated them -entered the correct statistical test

• entered the appropriate condition for each experiment submitting the curation for a second review, Thank you!