search

waldronlab / BugSigDBcuration

For documenting issues related to BugSigDB curation.
10 stars 4 forks source link

Profiles and diagnostic value of intestinal microbiota in schizophrenia patients with metabolic syndrome #423

Closed SvetlanaUP closed 1 month ago

SvetlanaUP commented 2 months ago

Profiles and diagnostic value of intestinal microbiota in schizophrenia patients with metabolic syndrome - Mengjuan Xing et al. – Frontiers in Endocrinology https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1190954/full

eve10111 commented 2 months ago

Hi @SvetlanaUP , can you kindly assign this paper to me? Thank you

eve10111 commented 2 months ago

@SvetlanaUP Accepted.. Thank you very much..

eve10111 commented 1 month ago

Hello @SvetlanaUP, Can you kindly review my curation! Link: https://bugsigdb.org/Study_1090 Thank you.

Scholarpat commented 1 month ago

Hi @eve10111,

This is a nice attempt. However, I noticed some inconsistencies that need to be addressed:

  1. Study Design: The study follows a cross-sectional design, not a time-series design. Time-series studies involve repeated observations of the same participants over time, which is not the case here.

  2. Condition: The condition contrasted in the study is Metabolic Syndrome (MetS), not Schizophrenia.

  3. Group Names: The correct names should be 'Schizophrenia patients without MetS' for Group 0 and 'Schizophrenia patients with MetS' for Group 1. There are no healthy controls in the study. Additionally, please recheck the group sizes, as they seem to have been interchanged in your curation.

  4. Matched on: The patients were not matched on any variables.

  5. Alpha Diversity: Both the Shannon and Simpson indices show an increase.

  6. Signature: Fig. 4A should be used as the source for the signature instead.

Please make these changes. Well done on your work so far!

Scholarpat commented 1 month ago

Hi @SvetlanaUP,

Here are the changes I made:

This curation is now complete. Please kindly delete experiment 2, as the study has only one experiment.

Thank you!

SvetlanaUP commented 1 month ago

https://bugsigdb.org/Study_1090 reviewed.

eve10111 commented 1 month ago

Hi @Scholarpat .. thank you so much. Corrections noted for future curation.