Multi-omics profiles of the intestinal microbiome in irritable bowel syndrome and its bowel habit subtypes

[cmirzayi]

Jacobs, J.P., Lagishetty, V., Hauer, M.C. et al. Multi-omics profiles of the intestinal microbiome in irritable bowel syndrome and its bowel habit subtypes. Microbiome 11, 5 (2023). https://doi.org/10.1186/s40168-022-01450-5

https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-022-01450-5

[Win2som]

Hi, my name is Chisom Obidike. I would love to curate this study.

[cmirzayi]

Assigned.

[Win2som]

Hello @cmirzayi I have completed my curation. Please review https://bugsigdb.org/Study_833

[Win2som]

Hi @lwaldron @cmirzayi @SvetlanaUP I finished my curation: https://bugsigdb.org/Study_833. Needs review.

[SvetlanaUP]

Marked as ready for review.

[cmirzayi]

Good job. Figure 2A also should be curated since it also presents differential abundance results. Also Figure 2B uses metatranscriptomics so you need to ensure you're curating the sequencing correctly for the 16S vs. metatranscriptomic methods. Fig 2A used 16S and 2B used metatranscriptomics so this confusion cost you a couple points.

Item	Description	max	points
1	All elements marked "Needs review" (none "Incomplete")	1	1
2	Correct study design	1	1
3	Entered all relevant experiments and no irrelevant experiments	1	0
4	Body site correctly identified (i.e. does not include multiple sites)	1	1
5	Condition entered according to contrast (correct EFO ontology)	1	1
6	Contrast groups correctly identified	1	1
7	Groups correctly labeled as 1 and 0 (1=cases, 0=controls)	1	1
8	Antibiotic exclusion correctly identified	1	0
9	Correctly identified sequencing details	2	1
10	Identified correct statistical test	1	0
11	Identified MHT correction	1	1
12	Correctly recorded matched on factors	1	1
13	Entered correct number of statistical tests per experiment	1	0
14	All diversity measures identified	1	1
15	Diversity results correctly entered as increased/decreased/unchanged	1	1
16	All signature sources correctly identified (-1 for each error)	2	1
17	Abundance direction correctly selected	1	1
18	Members of Signatures identified correctly	2	2
19	Correct use of NCBI taxonomy	2	2
	TOTAL	23	17

[Peacesandy]

Reviewed