webyrd / mediKanren

Proof-of-concept for reasoning over the SemMedDB knowledge base, using miniKanren + heuristics + indexing.
MIT License
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How to construct queries #23

Open ShrutiMarwaha opened 5 years ago

ShrutiMarwaha commented 5 years ago

Hi Developers,

I am trying to use Medikanren for generating hypothesis for drug repurposing. I was able to install the tool but I am not able to construct meaningful queries using GUI or programmatically. I have looked tacrine.rkt and other study-*.rkt files in the code directory for examples. How did you construct these queries? Manually?

Can you give some simple examples?

Looking at tacrine.rkt, how should I find connections between tacrine and alzheimer's disease using GUI? How should I find drugs that would decrease a gene ‘X’ that has Gain of function mutation in a (undiagnosed) rare disease.

Thanks, Shruti