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weizhouUMICH / SAIGE

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pheweb.sph.umich.edu server is down? #221

Closed Shicheng-Guo closed 2 years ago

Shicheng-Guo commented 4 years ago

Dear Dr. Zhou,

I find website pheweb.sph.umich.edu can not be accessed. Can you make a check to the server? another question is I am wondering is there any links to download the summary statistics of pheweb.sph.umich.edu.

Thanks.

Shicheng

weizhouUMICH commented 4 years ago

Dear Shicheng,

Thank you for using the UKBB SAIGE PheWeb! The summary statistics can be downloaded from here ftp://anonymous@share.sph.umich.edu/UKBB_SAIGE_HRC .

Btw, folks from the Broad Institute have recently run UKBB using SAIGE on > 7000 phenotypes, including PheCode ones, for all six ancestry samples, which may be also useful for your project. https://pan.ukbb.broadinstitute.org/ The summary stats can be downloaded from https://pan.ukbb.broadinstitute.org/downloads

Please feel free to let me know if you have any questions. Thanks, Wei

Shicheng-Guo commented 4 years ago

Dear Wei,

Thank you so much for the information about Broad Pan-UKB pheWAS project which is really helpful!!

Best,

Shicheng

Shicheng-Guo commented 4 years ago

Dear Wei,

Do you know is there any pheWeb service to show gene-based association result to UKBB dataset?

Thanks

Shicheng

weizhouUMICH commented 4 years ago

Hi Shicheng,

We have run gene-based tests for UK-Biobank 50k WES data for 791 binary phenotypes. Here is the browser: http://ukb-50kexome.leelabsg.org/ and the manuscript (Zhao et al, 2020) https://www.sciencedirect.com/science/article/pii/S0002929719304331

Thanks, Wei