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welch-lab / MultiVelo

Multi-omic velocity inference
BSD 3-Clause "New" or "Revised" License
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'multivelo.velocity_embedding_stream' plotting #16

Open WangRong423 opened 1 year ago

WangRong423 commented 1 year ago

Hi,danie I want to see groups of cells (time points, individuals, etc.) mapped separately in the same velocity stream UMAP to compare the orientation and proportion of the cells in different states. Is there any way to do that? similar to the picture below plot

danielee0707 commented 1 year ago

Because I don't know the detail of your analysis, I cannot propose a method that guarantees to work. I imagine that it requires some batch correction and joint velocity inference. Concatenating two separately inferred velocity matrices to find a joint cell transition map may also work if normalization is done carefully.