This has happened to me three times: The game crashes (not entirely because the mouse hover over still works with the icons at the top right of the screen, but not clicking the buttons does not work) randomly without and error warning. The game is totally unresponsive. This means perhaps this is not an error but a rare event that occurs. Did you set up a hotkey that opens up the options menu by any chance?
This has happened to me three times: The game crashes (not entirely because the mouse hover over still works with the icons at the top right of the screen, but not clicking the buttons does not work) randomly without and error warning. The game is totally unresponsive. This means perhaps this is not an error but a rare event that occurs. Did you set up a hotkey that opens up the options menu by any chance?