Show how to estimate shape parameter from an auxiliary dataset

willtownes / quminorm

Turning the quasi-UMI method into a bioconductor package

GNU Lesser General Public License v3.0

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Show how to estimate shape parameter from an auxiliary dataset #1

Closed willtownes closed 4 years ago

willtownes commented 4 years ago

As a user with UMI data in a SingleCellExperiment, I can fit the Poisson-lognormal MLEs for all cells so that I can determine a reasonable custom shape parameter for applying QUMI normalization to my non-UMI data of the same tissue type.

make sure the functionality exists in the code base
demonstrate it in a vignette

willtownes commented 4 years ago

this is now in the vignette