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wouterpeyrot / CCGWAS

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ccGWAS for continuous traits #13

Closed ferfacal92 closed 9 months ago

ferfacal92 commented 1 year ago

Hello! I wonder if I can use ccGWAS for association testing between a dichotomous trait (for example, diabetes mellitus vs controls) and a continuos one (for example, body mass index).

Thank you in advance, Fernando

wouterpeyrot commented 1 year ago

Hi Fernando, no this is not possible (CC-GWAS compares the allele frequencies across two groups of cases), unless you want to dichotomous BMI so this also gets case group (e.g. obesity)

ferfacal92 commented 1 year ago

Thak you for your answer!

Fernando

De: Wouter Peyrot @.> Enviado: jueves, 20 de julio de 2023 10:20 Para: wouterpeyrot/CCGWAS @.> Cc: ferfacal92 @.>; Author @.> Asunto: Re: [wouterpeyrot/CCGWAS] ccGWAS for continuous traits (Issue #13)

Hi Fernando, no this is not possible (CC-GWAS compares the allele frequencies across two groups of cases), unless you want to dichotomous BMI so this also gets case group (e.g. obesity)

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