Closed xonq closed 1 month ago
You can't run ClonalFrameML directly on the output of Mauve. You need to first extract the core of the alignment, ie the regions that are shared by all genomes. There is a tool to do exactly that in the Mauve suite called stripsubsetLCBs. Cf issue #29 where I gave links to it, but these seem to now be broken. I don't know if stripsubsetLCBs is still available or if there is something else you could use to do the same.
Thank you for your response, I can confirm stripSubsetLCBs
is part of the mauveAlign
package and I was able to get ClonalFrameML working.
I am running into an ambiguous segmentation fault during or directly following reading the newick file.
The alignment is directly from ProgressiveMauve output. The phylogeny is generated from IQ-TREE2. I removed bootstrap values from the newick and converted the tip names to correspond to the XMFA headers.
output:
command:
input files: mauve.xmfa final.phylo.newick