microsatellites located at some large mutation regions may be estameated as unstable one

xjtu-omics / msisensor-pro

Microsatellite Instability (MSI) detection using high-throughput sequencing data.

Other

93 stars 20 forks source link

microsatellites located at some large mutation regions may be estameated as unstable one #13

Open PengJia6 opened 3 years ago

PengJia6 commented 3 years ago

Microsatellites located at some large mutation regions (such as loss of heterozygosity (LOH)) in tumor sample may be estameated as unstable sites for MSI detection. In this case, MSS sample may be misjudged as MSI one.