How to classify the MSI high and MSI low ?

xjtu-omics / msisensor-pro

Microsatellite Instability (MSI) detection using high-throughput sequencing data.

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How to classify the MSI high and MSI low ? #37

Open wangxiaoshine opened 2 years ago

wangxiaoshine commented 2 years ago

How to classify the MSI high and MSI low ? Looking forward to your reply.

PengJia6 commented 2 years ago

In MSIsensor-pro, we did not provide a cut-off, because the cut-off will be different for different sequencing panel. If you want to use MSIsensor-pro in a new panel for only tumor sample MSI detection, please use the msi status from msisensor or gold standard as true value to obtain a cut-off suit for your panel. By the way, it seems that MSI is a continuous value, and you can just use msi score for you research.