Hi Xu Ran
Many thanks for developing MuSiC! I really like the idea of giving each gene a weight instead of establishing an overall cutoff w signature matrix.
I am currently quite new to learning deconvolution techniques and R as well and I hope you can help my understanding on it.
1-for the QC of scRNAseq data/ i was wondering how does MuSiC filter off the doublets/multiplets/dying cells and outliers that might give falsely high gene expression.
2-I read over your code the part where it says..
> GSE50244.EMTAB.prop
I couldnt find the assignment of this variable. I'm guessing the GSE50244 set was concatenated with
EMTAB set but it is not clear to me what are the intermediate steps to it.
Hi Xu Ran Many thanks for developing MuSiC! I really like the idea of giving each gene a weight instead of establishing an overall cutoff w signature matrix.
I am currently quite new to learning deconvolution techniques and R as well and I hope you can help my understanding on it. 1-for the QC of scRNAseq data/ i was wondering how does MuSiC filter off the doublets/multiplets/dying cells and outliers that might give falsely high gene expression.
2-I read over your code the part where it says..
> GSE50244.EMTAB.propI couldnt find the assignment of this variable. I'm guessing the GSE50244 set was concatenated with EMTAB set but it is not clear to me what are the intermediate steps to it.Thank you