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xuranw / MuSiC

Multi-subject Single Cell Deconvolution
https://github.com/xuranw/MuSiC
GNU General Public License v3.0
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Does normalized expression data work well? #62

Open yingyonghui opened 3 years ago

yingyonghui commented 3 years ago

Thanks for your amazing tool for deconvolution of bulk seq data. I now just want to deconvolute the TCGA bulk data based on a scRNA-seq reference data, and I have only the normalized expression data in log scale. I'm wondering whether MuSic work well when applied on the normalized input data?

Many thanks! Yonghui

kabirium commented 3 years ago

Hi, did you ever find the answer to this question? I have CPM bulk data and had the same doubt.