xuranw / MuSiC

Multi-subject Single Cell Deconvolution
https://github.com/xuranw/MuSiC
GNU General Public License v3.0
220 stars 83 forks source link

question about single cell reference #97

Open sadiexiaoyu opened 1 year ago

sadiexiaoyu commented 1 year ago

Hi, Thank you for the cool software! I have a question about which cell type should be used as the reference.

For example, I tried different ways by using different sets of cell types retrieved from the same data, and got different cell proportions. 1) all cell types retrieved from integrated data from multiple tissues. 2) cell types from certain tissues. 3) only target interested cell types.

Could you please give me any suggestion? Thanks in advance!