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xzhoulab / iDEA

Differential expression (DE); gene set Enrichment Analysis (GSEA); single cell RNAseq studies (scRNAseq)
GNU General Public License v3.0
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Order of running iDEA.BMA() and iDEA.fit(modelVariant = T) after running iDEA.fit(modelVariant = F)? #27

Open denvercal1234GitHub opened 1 month ago

denvercal1234GitHub commented 1 month ago

Hi there,

Thank you very much for the tool.

I was hoping to get clarification regarding the order in which one should run iDEA.BMA() and the variant iDEA.fit model.

After running iDEA.fit (modelVariant = F) followed by iDEA.louis(), do I need to create a new idea object to run iDEA.BMA()?

Similarly, do I need a new object if I want to compare the "original" model and the variant model by running iDEA.fit(modelVariant = F)?

Thank you for your help!