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yancychy / DiffChIPL

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Without Reps #4

Open BennyHz opened 6 months ago

BennyHz commented 6 months ago

Hi! I wander if it's possible to run DiffChIPL without replication？

yancychy commented 6 months ago

No. DiffChIPL can not do it. But after you extract raw count data for each peak, you can use edgeR to compare single replicate. https://www.bioconductor.org/packages/release/bioc/vignettes/edgeR/inst/doc/edgeRUsersGuide.pdf

2.12 What to do if you have no replicates .