Didn't know of a better place to post this so putting it here (if there's one let me know)
I've noticed a lot of reversions in position S:127 in JN.1 recently. These are coming from particular labs, mostly Canada-ON, but also some others that sequence less.
I don't know what's the root cause of this site being particular rich in reversions but it looks like it's an artefact - we've seen this many times before.
@AngieHinrichs it would be cool if you could see whether branch specific masking might help
If the reversions were real, we'd expect to see them cluster better.
Didn't know of a better place to post this so putting it here (if there's one let me know)
I've noticed a lot of reversions in position S:127 in JN.1 recently. These are coming from particular labs, mostly Canada-ON, but also some others that sequence less.
I don't know what's the root cause of this site being particular rich in reversions but it looks like it's an artefact - we've seen this many times before.
@AngieHinrichs it would be cool if you could see whether branch specific masking might help
If the reversions were real, we'd expect to see them cluster better.
This looks overwhelmingly fake:
https://cov-spectrum.org/explore/World/AllSamples/Past6M/variants?variantQuery=S%3A127V+%26+nextcladePangoLineage%3ABA.2.86*&nextcladePangoLineage1=BA.2.86*&