Do the input hic data and the assembly to be simulated have to be of the same species?

yezhengSTAT / FreeHiC

FreeHi-C pipeline for high fidelity Hi-C data simulation.

MIT License

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Do the input hic data and the assembly to be simulated have to be of the same species? #12

Open xujialupaoli opened 1 month ago

xujialupaoli commented 1 month ago

Thank you for the tool! I want to simulate a hic data for my E. coli. Do I have to use a hic data from E. coli as input for the simulation? Can I use the HIC data of human HG002 for the simulation?

yezhengSTAT commented 1 month ago

Hello,

Yes, FreeHiC will need the target E.coli Hi-C matrix as input to learn the interaction patterns. FreeHiC can only add randomness to the contacts.

Thanks, Ye