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yupenghe / methylpy

WGBS/NOMe-seq Data Processing & Differential Methylation Analysis
Apache License 2.0
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bam-quality-filter NOMe-seq #72

Open sherryxuePKU opened 3 years ago

sherryxuePKU commented 3 years ago

Hello, I wonder if methylpy can filter reads by the methylation level of HCH. Because I have some NOMe-seq data，however they appeared to have low bisulfite conversion rate. I want to filter the genomic reads by their mHCH, not mCH. By the way, it may be helpful to make mehylpy bam-quality filter command able to filter by a user-selected type of C?

yupenghe commented 3 years ago

Thanks for the suggestion. Unfortunately, this feature is not currently supported by methylpy yet and it is not trivial to implement. I cannot promise that this feature will be available in a short period of time.

sherryxuePKU commented 3 years ago

@yupenghe Thanks for your reply! I'm in no hurry to use this function. BTW, methylpy is very useful in my data~