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yupenghe / methylpy

WGBS/NOMe-seq Data Processing & Differential Methylation Analysis
Apache License 2.0
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mapping to a large genome #75

Open awieeeee opened 2 years ago

awieeeee commented 2 years ago

Dear yupenghe,

I would like to know to deal with organisms that have chromosomes more than 512Mb. During mapping, samtools index command failed with showing the error message. samtools index: failed to create index for "[sample].bam": Numerical result out of range

Thanks.

yupenghe commented 2 years ago

That should be fine. Methylpy works for human genome which is larger than 512Mb. Is the error reproducible? If so, having some files to reproduce the error will help me identify the issue.