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zavolanlab / htsinfer

Infer metadata for your downstream analysis straight from your RNA-seq data
Apache License 2.0
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refactor: reduce memory usage of comparing alignments #158

Open balajtimate opened 5 months ago

balajtimate commented 5 months ago

Is your feature request related to a problem? Please describe. Currently, the _align_mates function in get_library_type.py uses a lot of memory to store the alignments from both input samples and compare them to find concordant mates.

Describe the solution you'd like Implement a memory-efficient solution to compare alignments on the fly without the need to actually store both alignments in memory.