The human reference genome has been improved these years and the latest one would be hg38 or GRCh38. Therefore, we decided to generate the input BAM file aligned with hg38 rather than hg37. As hg37 was applied as the reference genome in the original paper, may I ask if we could use TelSeq directly on the hg38 BAM file without any extra code added? Is there a difference in the results? Thank you.
Hi,
The human reference genome has been improved these years and the latest one would be hg38 or GRCh38. Therefore, we decided to generate the input BAM file aligned with hg38 rather than hg37. As hg37 was applied as the reference genome in the original paper, may I ask if we could use TelSeq directly on the hg38 BAM file without any extra code added? Is there a difference in the results? Thank you.