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zeeev / mergeSVcallers

heuristics to merge structural variant calls in VCF format.
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How does merging work? #5

Closed djakubosky closed 4 years ago

djakubosky commented 7 years ago

Hi! glad to see a tool for this purpose, merging call sets is a headache. I am curious as to whether this tool will merge based on correlation between samples, is there any criteria for a merge other than distance and overlap?

Thanks!

zeeev commented 7 years ago

@djakubosky you can merge within samples and then merge across datasets. Does that answer your question?

djakubosky commented 4 years ago

So basically, the method doesn't consider correlation of genotypes between samples, but rather overlap of SVs both within and between samples to create a single set of less "redundant" positions.