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zktuong / dandelion

dandelion - A single cell BCR/TCR V(D)J-seq analysis package for 10X Chromium 5' data
https://sc-dandelion.readthedocs.io/
GNU Affero General Public License v3.0
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Restore global pairwise distance calculation #217

Open zktuong opened 1 year ago

zktuong commented 1 year ago

Description of the issue

Wither version 0.2.4 onwards, the decision was to speed up the calculation only per clone, but i would like to try and reimplement a global pairwise distance calculation.

Perhaps i could try tcrdist3's approach with pwseqdist?

zktuong commented 1 year ago

this might be a partial solution to #219, can use umap afterwards?