Some literature on the fish spinal cord regarding the physiological properties and cell types at the specific developmental stage we are looking at. In particular, Tong et al, 2012 gives a good examination of the biophysical properties of the IC cells (supposedly pace makers), and Saint-Amant 2001 gives an overview of the type of connectivity between cell types in the circuit.
Reviews like Blankenship and Feller 2010 is good regarding the general principles observed in many different spontaneous activity models, but CPGs in different animals are wired up quite differently in terms of cell type components and neurotransmitters, and some cell types/synapses may only become functional later in development. We are definitely open to all the suggested models but hopefully the specific literatures on fish embryonic spinal cord can help narrowing down the potential mechanisms.
Some literature on the fish spinal cord regarding the physiological properties and cell types at the specific developmental stage we are looking at. In particular, Tong et al, 2012 gives a good examination of the biophysical properties of the IC cells (supposedly pace makers), and Saint-Amant 2001 gives an overview of the type of connectivity between cell types in the circuit.
Reviews like Blankenship and Feller 2010 is good regarding the general principles observed in many different spontaneous activity models, but CPGs in different animals are wired up quite differently in terms of cell type components and neurotransmitters, and some cell types/synapses may only become functional later in development. We are definitely open to all the suggested models but hopefully the specific literatures on fish embryonic spinal cord can help narrowing down the potential mechanisms.
zebrafishspinalcordliterature.zip