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Dear @msevestre, @JLPangloss, @RBurghaus, @Yuri05,
Recently our articel "Gene Expression Databases for PBPK modeling of humans & animal species" was accepted in CPT: Pharmacometrics & Systems Phar…
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Hello,
I recently developed a PBPK model using PK Sim for a drug with a Log P of 2. My goal was to predict the concentration of the drug in lung tissue after oral administration of this drug. However…
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1. Import a PBPK model into MoBi (v12)
2. Open the SS-BB and save the the organ "Muscle" via "Save With Individual..."
3. Create a new module "Tumor"
4. Try to load the exported organ in the SS-BB …
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This issue addresses two situations where the model diagram disappears, what forces the user to switch to code view and solve the problem. The first seems a bug, whereas the second could be perhaps av…
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[esqLABS utilities package • esqlabsR](https://esqlabs.github.io/esqlabsR/) --> in the second paragraph, PBK --> PBPK
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I have been trying to build a PBPK model for asenapine in rats, since there are no readily available databases for rats as there are for humans, can someone please suggest me ways to gets the relative…
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Should we maybe list all models included in a certain release in its description?
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Structures of PBPK Models across species are not consistent (unexpectedly!!). Animals differ from Human in 2 major parts of the model:
- GI Tract
- Glomerular filtration
- … and the missing (in a…
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Is there any option of changing the gastric emptying time in a simulation designed for population?
For example: I am working on a Drug Interaction model, when two models are coupled for interaction …
HTQ05 updated
10 months ago