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**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Load from file: [System merge sequences while replacing selected monomers from the library in view mode.zip](https://github.com…
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**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Go to RNA builder and create preset without base (name it "No base")
![image](https://github.com/user-attachments/assets/334c0…
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**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Load from file: [System allow to change monomers on the canvase in view mode (that is not allowed).zip](https://github.com/user…
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Time: January 24th (12 noon UK, 1pm EU, 11pm Aus) [Timezones](https://www.timeanddate.com/worldclock/meetingdetails.html?year=2022&month=11&day=22&hour=12&min=0&sec=0&p1=43&p2=136&p3=37&p4=771&p5=235&…
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**Steps to Reproduce**
1. Go to Macromolecules - Flex mode
2. Load from file: [Sequence with R1-R2 connections between Bases and Peptides causes crash to white screen.zip](https://github.com/user-at…
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**NOTE:** Very common problem with all types of monomer
**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Load from file: [Replacement of preset at the begining of sequence o…
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**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Load from file: [Uploading Replacement of preset at the end of sequence on preset wout base works wrong.zip…]()
![image](https…
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**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Load from file: [Replacement of peptide at the end on preset w_out phosphate works wrong.zip](https://github.com/user-attachmen…
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**Background**
Current js bundle size of Ketcher is 6.5MB. It leads to long initial ketcher loading time.
**Solution**
It needs to run bundle analyser and investigate options to reduce bundle siz…
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**Steps to Reproduce**
1. Go to Macromolecules mode - Sequence mode
2. Go to the Library - Peptide tab
3. Click on `A` peptide twice to put two `A`s on the canvas
![image](https://github.com/user-…