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Hi Vladimir,
Thanks for making this awesome model. I am very impressed and interested in the results.
In the readme, you mentioned 2 types of background, synonymous mutations and non-coding on…
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Hi @tfabiha, here is the discussion for the memory issue of our region extraction pipeline.
> To do list:
- [ ] Fabiha: To reproduce both versions and see if she can get an idea based on both…
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Hi there.
According to the UKBB tutorial, I was a little bit confused.
Can I build the Step 1 prediction model for each chromosome (and run Step 2 for each chromosome using the chromosome-level …
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Dear author,
Hope this issue alert finds you well.
I am running the function read_ukb_tabdata(fukbtab,dfhtml,fields_to_keep = baseline_fields) to extract the variables following the code:
bas…
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Hello @anglixue,
I have been trying to run mtCOJO on a trait, adjusting for 3 other traits using GCTA v1.94.1 and this is the error message I received:
```
Error: the variance-covariance matrix o…
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I am trying to porting the visualization of the source code [L1-regularized logistic regression models for predicting asthma](https://github.com/tdhock/hla-asthma/blob/a3dc13ac5a02302b75eb59538b6c8f63…
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We have methods for associating individual genetic variants and phenotypes (https://github.com/pystatgen/sgkit/pull/16, https://github.com/pystatgen/sgkit/pull/66), but inferring associations with gen…
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Hi! I like topr a lot and hopefully will be using it in future manuscrips!
Right now I am struggling with locuszoom, because as many SNPs besides my "target" are in perfect LD with this target, the…
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HI GCTA developer,
Thanks for the great tool! I ran gcta --reml on UKB data with 64 cores and 512G memory and got the following error:
> Accepted options:
--reml
--grm all ###all.grm.bin is …
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Just adding this (obvious) issue so that we have somewhere to keep track of this discussion on this. Perhaps @awohns can add a little explanation about what the critical sticking points are?