-
Hi!
This isn't really an issue. In your paper "Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate", you mention simulation of WGBS data. I was wondering …
-
Hi,
I was trying to identify the DMRs using methylpy. But the results file is empty with just header.
The command and its output are here.
```
>methylpy DMRfind --allc-files allc_temp17.tsv…
-
Update the following URL to point to the GitHub repository of
the package you wish to submit to _Bioconductor_
- Repository: https://github.com/YuLab-SMU/GeoTcgaData
Confirm the following by ed…
-
Now that bam files have standardized on including modified base information, with per-read data, is it possible for you to create an importing subroutine that can handle .bam input. Or can you suggest…
-
Over the past year or so, we have done some restructuring. This has resulted in a few changes for classes is the derived mapping file.
We should review these changes to make sure they are appropria…
-
Hello, @alexg9010
I met a problem about MethylKit recently.
You know there are two key steps like below:
1). myDiff_new = calculateDiffMeth(meth_new, covariates = covariates, overdispersion="…
-
Hi,
I am using methylkit for my RRBS data. I do have some covariates too which I want to use and check their effect to in our treatments too.
I have generated few cluster figure and did some experim…
-
Hello,
### I used TCA to identify cell-type significantly differentially methylated CpGs between two exposure groups (approximately 32 in each group). In order to visualize the spread of dat…
-
https://mp.weixin.qq.com/s/FoEi0FiYOubUyVMZp-F0bw
-
Dear developers,
I am running the github version of boostme and I get the following error:
` size must be less or equal than 180249 (size of data), set replace = TRUE to use sampling with replac…