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Hi Kai,
thanks for your tool on cross-ancestry fine-mapping!
Currently I'm trying to do cross-ancestry fine-mapping for two ancestries and both GWASs are performed with the same set of covaria…
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Hello, thank you for the nice work. I am trying to run GENESIS on a few GWASs, and I am a bit confused with some of the parameter setting:
1) the input should includes the effective sample size, de…
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In the two sample files 1_oa2016_hm3samp_neur.txt and 1_oa2016_hm3samp_swb.txt you gave me, I don't know exactly how to get the N value, and I still don't fully understand it after reading relevant li…
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Dear author,
Another issue came along as I was using bGWAS (as in the title and below). I have checked the two ZMatrices files manually. There are large amount of SNPs in common among the gwas stud…
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Hi users and developers,
After the use of MTAG the mean chi2 of TRAIT_1 increased from 1.088 to 1.417.
According to the increase of mean chi (1-mean chi^2 MTAG)/(1-mean chi^2 GWAS), my GWAS equ…
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Hi there,
I am running mgta using two traits and ~1 million of markers.
I met the following error:
2020/05/05/09:38:55 AM
MTAG: Multi-trait Analysis of GWAS
Version: 1.0.8
(C) 2017 …
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I've been able to run MTAG and get results without any problems before. Only when I use GCST009379 on the GWAS catalog as trait1, it gives me an error no matter which GWAS I use for trait2. The error …
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Hello,
I am trying to calculate a PRS-score, with PRSice2, on a case-control-cohort based on summary statistics from a larger GWAS-study. I have calculated principal components and want to use the fi…
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Hi I'm trying to run MTAG on 93 traits simultaneously...
After Munging and Merging the log was the following:
> .....
> 2018/10/02/02:28:26 PM Dropped 0 SNPs due to strand ambiguity, 1915103 SN…
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Hello,
I ran the --blup option and I obtained a Beta for each trait that I used in the meta-analysis.
Is there another option to compute also the SE?
Also my understanding from some of the previ…