-
I looked up KANSL1 in gnomAD v4.1.0 (non-UKB) https://gnomad.broadinstitute.org/gene/ENSG00000120071?dataset=gnomad_r4_non_ukb. I selected pLoF only variants and wanted to export variants to CSV.
Cli…
-
I am attempting fine-mapping on a GWAS, and have significant hits on 2 chromosomes, which I have been analyzing separately. My fitted model will not converge after 100 iterations. I have checked the l…
-
@alhanster
Change
source("~/Desktop/Scripts/UKB_MTR.R")
to
source("scripts/UKB_MTR.R")
-
Alkes price lab moved their data to Google Storage. This is....not great, because it may mean all the data is now behind a paywall.
https://alkesgroup.broadinstitute.org/UKBB_LD/
Will see if I c…
-
I have setup as following (running on a custom port, not 8007). I'm happy to provide an access/secret key for my Backblaze B2 instance for testing.
Error: `create storage failed: s3pbs: error fetch…
-
Hi,
I am trying to impute a small region on chromosome 21 using a custom reference panel of ~500 individuals. I receive the following error:
```
$ ssimp-linux-0.3 \
> --gwas chr21chunk.txt \
…
-
Hi there~ I have a tough question. I'm using the Array LD reference panel, but when I complete all the steps and do the final HDL, it says, "It seems this directory does not contain all the files need…
-
Hey, any chance you can upload a subset of the uk bio bank data for testing?
Thnx!
-
I used the following code to calculate PGS for my UK biobank research by PGS003765 research results, and successfully obtained the result, but my variants matched only 12.9%. Is this normal? Previous…
-
The default designs in SR2 have never been particularly impressive, to the point that I don't think anyone uses their starter ships for anything except scouting (unless they retrofit them, but this op…