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PMID: 10026162 shows that the rat LPHN3 protein does not bind latrophilin. This corresponds to UniProt:Q9Z173. Therefore we need to remove the:
InterPro:IPR003924 GPCR, family 2, latrophilin > GO:…
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Should latrotoxin receptor move to become a child of MF:
transmembrane receptor?
From what an editor has read, alpha-latrotoxin may bind
a seven transmembrane protein (but it is not clear it
has b…
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Hi (Paola?),
sorry, this is am long one!
I’ve been making several new GPCR related complexes and noticed some holes and inconsistencies in the GO. The main problem lies in the CC branch but I will n…
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Hi,
There are missing links and relationships in the Neurotrophin TRK receptor signalling pathway and Brain-derived neurotrophic factor receptor signalling pathway. I am attaching a figure of how thi…
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Hi GO team,
Below is the description of the suggested terms, respective GO IDs, and the supporting pubmed id.
Suggested terms:
ligand-dependent GPCR activity (from pubmed id: 17379646)(new child ter…
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HI
looking at the definition of GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway
Any process that increases the frequency, rate or extent of adenylate cycla…
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Hi,
looking for the right way to name an inhibitor of G-protein, I found some inconsistencies in this family:
The term
GO:0001647; G-protein coupled cytokinin receptor activity
should be simply modi…
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New term request: short neuropeptide F receptor activity
Is_a child of GO:0008188 neuropeptide receptor activity
To annotate short neuropeptide-activated GPCRs
Short neuropeptide F (sNPF) peptides …
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These terms have both G-protein coupled receptor,
unknown ligand[16526] and
rhodopsin-like receptor[1584] as parents. However, some
forms of
leukotriene, nociceptin, platelet ADP receptors and
leuc…
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These terms have both G-protein coupled receptor,
unknown ligand[16526] and
rhodopsin-like receptor[1584] as parents. However, some
forms of
leukotriene, nociceptin, platelet ADP receptors and
leuc…