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Would this be able to pull large ODEs from model objects?
In particular, ones used in the MRGsolve package?
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@kylebaron Hi Kyle, I'm trying to optimize two parameters of my PBPK model against some observed data (**11 mean concentration data points**). The codes are as follow:
```
data% unlist %>% unname
y…
FanWn updated
2 years ago
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Hi all,
To my knowledge this is the first data that quantifies the expression of transporters in the kidney for all species (Basit et al., 2019, doi: 10.1124/dmd.119.086579). Units are presented in…
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I created a PBPK model in PK Sim v11, saved it, and exported to MoBi for additional modification. Whenever I try to re-open the original PK Sim file, I get the error below. Please advise.
Thanks,
…
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The code format of a .mo file is not kept after modifying the property of a graphic element (an arrow) in the icon view of the modelica class.
It occurs in OMEdit 1.21 both in Windows 10 and Windo…
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과정 | 이수구분 | 학수번호 | 교과목명 | | 학점 | 요일 | 교시 | 담당교수 | 강의실
-- | -- | -- | -- | -- | -- | -- | -- | -- | --
석사 | 초독 | Mpha501 | 석사초독 | | 1 | 금 | 1 | 임동석 | 약리학세미나실
석사 | 필수 | - | 코딩을 활용한 PK/PD 자료처리 | …
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hi @kylebmetrum -
What parts are missing to be able to simulate a transit curve? Not sure about the following
1. is `lgamma` in the correct representation in the depot compartment?
2. not sur…
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When "Calculate Scale Divisor" is used after simulation, the Start values of the molecules appear to be set to NaN.
Use the (internal) example project provided in Mantis, then:
1. Open the simulat…
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Dear all,
In the unspecified liver clearance process in PK-Sim, the intrinsic clearance for the liver is calculated using several parameters, one of them being referred to as **Plasma clearance**. …
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Eur J Pharm Biopharm. 2020 Sep 14;S0939-6411(20)30283-6.
Johanna Eriksson, Helena Thörn, Hans Lennernäs, Erik Sjögren
https://pubmed.ncbi.nlm.nih.gov/32941997/
Abstract
Systemic exposure of in…