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In the paper I am curating they performed a huge screen (two mutants + wt and tested their sensitivity to 1200 compounds). It seems a bit crazy to add 1200 rows to the gene pages so I have just picked…
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Hi
the following error has been reported by a user (Igor Pamirskiy; parimski@mail.ru) who has stated that
"In the description of Silicatein alpha (and other silicateins) in the
"Ontologies"/"Molecul…
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This term and some relatives are showing as subset prokaryotes. While there is recent evidence for activities/processes similar to protein ubiquitinylation in bacteria, Ub is absent.
Reported by: jim…
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NTR: deneddylase activity
Dear GO Editors,
BP terms exist for cullin deneddylation (GO:0010388) but none seem to exist in the MF category forthis activity. PMID:23408908, Figure 4 describes the dene…
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Hi
I'd like to suggest a new GO term 'negative regulation of peptidase activity in other organism'.
It would be similar to GO:0052180 'negative regulation of peptidase activity in other organism in…
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Hi
fifth term request to enable appropriate annotation of CST3 P01034
(Cystatin C). CST3 is a cysteine protease inhibitor. As such it inhibits
several elastase and collagenases, including cathepsins.…
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I want to annotate pombe aspartyl amino peptidae
PMID:20044953
But
OBSOLETE. Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.
what sh…
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Hello,
I have doubts about the definition of "ubiquitin thiolesterase activity": Catalysis of the reaction: ubiquitin C-terminal thiolester + H2O = ubiquitin + a thiol. Hydrolysis of esters, includi…
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PINK1-PARKIN dependent mitophagy pathway
Human PINK1 Q9BXM7
Human Parkin O60260
Specifically, in PMID: 24821430 it is stated that:
“…when a dysfunctional mitochondrion cannot be repaired, it is cl…
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Hi
Fourth term request to enable appropriate annotation of CST3 P01034 (Cystatin C). CST3 is a cysteine protease inhibitor. As such it inhibits several elastase and collagenases, including cathepsins…