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Figure 1 in PMID:25898166 shows that knock down of PICALM Q13492 in cultured cells results in an increase in size of clathrin-coated vesicles and in reduced ability to 'close' the vesicles being forme…
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Hi,
I have just finished processing sequencing data obtained with MinION and noticed something.
In the past Nanopolish was giving me a lot of indels, that I just ignored. This last time though, no…
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Hello Prof. Richard Neher @rneher
If I want to obtain all single-copy genes that are present in all the studying genomes, which alignment files should I use? (given that I use the default 1.0 for …
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Update the following URL to point to the GitHub repository of
the package you wish to submit to _Bioconductor_
- Repository: https://github.com/ruggleslab/blacksheepr
Confirm the following by e…
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Hi,
We are having troubles understanding why our sequences are marked as unproductive. The antibody sequences have been validated experimentally and Sanger sequenced to ensure they are certainly prod…
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Dear Dr. Rhys Farrer,
I am trying to generate synteny plots for chromosomal duplication for our new genome (non-model organism). For this I am trying to look for gene duplication of MYB genes in ba…
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Hello,
I have a question about duplication rates when generating genomes.
The wiki [(here)](https://github.com/AADavin/ZOMBI/wiki/Generating-Genomes#basic-mode-g) says that
> The rates are gen…
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In SearchGUI, we have a user appending a source tag -- sihumi_ -- in their FASTA header line:
`>sp|sihumi_Q8AAB1| GLMS_BACTN Glutamine--fructose-6-phosphate aminotransferase [isomerizing] OS=Bacteroi…
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Hi Brent,
I encounter the error below when annotating a vcf of structural variants, obtained using SURVIVOR merge of two input vcfs. The command is `vcfanno -ends -p 8 vcfanno_conf.toml {input} > {…
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During review of some of our 100KGP candidates based on "known" disease genes it has come to light that a number are based on Orphanet evidence only and further exploration shows they involve disease-…