![GitHub contributors](https://img.shields.io/github/contributors/AllenInstitute/MIES?style=plastic)
MIES is a proven [1,
2,
3,
4,
5,
6] sweep based data acquisition
software package for intracellular electrophysiology (patch clamp). It offers
top of its class flexibility and robustness for stimulus generation, data
acquisition, and analysis.
Highlights
- Acquire data on up to eight headstage on a single DAC.
- Run up to five DACs in parallel.
- Create arbitrarily complex stimulus sets with an easy to use GUI
- Export all data, including all of its metadata, into the industry-standard NWBv2-format and read it back in
- Run custom code during data acquisition for Automatic Experiment Control
- Completely automate the experimental setup using JSON configuration files
- Interact with MIES from other programming languages (Python, C++, Javascript, ...) using ZeroMQ.
- Comprehensive experimental metadata acquisition and browsing tools
- Use the integrated scripting language for convenient on-the-fly data evaluation.
- Fully backward compatible with every earlier MIES version
![Slideshow showing the main graphical user interfaces of MIES in Igor Pro](https://github.com/AllenInstitute/MIES/raw/main/Packages/Artwork/readme-teaser.gif)
Supported Hardware
-
Digital to analog converters (DAC):
-
National Instruments:
Other NI hardware models can be added on request. Please open an issue from within MIES,
MIES Panels->Report an issue
, for that.
-
Instrutech/HEKA ITC:
ITC devices are at the End-Of-Service-Life (EOSL). National Instruments DACs are recommended for MIES users looking
for new hardware.
-
Amplifier: Molecular Devices 700B
-
Pressure control (optional): ITC 18/1600 or National Instruments USB 6001
Required Software
Acquisition
Data evaluation
- Windows 10x64 or MacOSX 10.10
Getting started
Support statement
The last released version receives fixes for all critical bugs.
Bug reporting
Instructions