The constitutional wgs pipeline is a versatile workflow used in both genome sequencing and panels. It is implemented in the Nextflow workflow-language and designed to run in a computational cluster environment, using Singularity containers to manage software dependencies.
The output is immediately importable into the software Scout, an open-source software for identifying variants with clinical significance.
In order to run it, you will need to have a Sentieon license.
If you run into any issues using this pipeline, open an issue in the GitHub repository.
Illustration of the pipeline, its steps and processes.